Features of diagnosis of generalized forms of meningococcal infection at present stage

Abstract

Despite the low level of morbidity, the significance of meningococcal infection (MI) persists and is primarily due to the predicted rise in morbidity after a long period of relative well-being (decline), instability of the serogroup landscape, an increase in morbidity caused by previously rare serotypes (meningococcus W), lack of routine vaccination, as well as severe course, the development of formidable complications and high risk of death. The risk of up to 30–60 % disabling complications after generalized forms of meningococcal infection (GFMI), including physical and neuropsychiatric problems, is also important. The reason for the unfavorable prognosis of the disease is the late diagnosis at the pre-hospital stage, hospitalization in non-core hospitals, the severity of the pathological process. With a low incidence, a wide range of antibacterial drugs, the mortality from GFMI is significant, from 6 to 14 %. The main means to significantly reduce the incidence and mortality from GFMI is currently the introduction of mass vaccination of the population against MI.