Abstract
By the WHO data,Ukraineis country number1 inEuropeand number2 inthe world according to the cardiovascular mortality rate. In the structure of the prevalence of cardiovascular diseases in Ukraine, the percentage of persons of working age with arterial hypertension is 36.7%. The improvement of the prognosis of patients with arterial hypertension depends not only on long-term effective control of blood pressure, but the diagnosis and initiation of therapy at the initial stage of the development of the disease, when the target organs have not yet undergone hypertensive damage is also an important condition. The article presents the results of neuropsychological examination of 509 outpatients with a controlled second stage arterial hypertension, with an integrated assessment of cognitive functions using the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MCA) methods. It has been established that even in patients with controlled arterial hypertension stage II with a low cardiovascular risk, by SCORE scale cognitive disorders were revealed in 32,2%. The peculiarities of the development of cognitive disorders in arterial hypertension in connection with the history and course of the disease are analyzed. The majority of patients with hypertension have an increased level of anxiety, especially personality, and this is not due to the presence or absence of cognitive disorders. In patients with hypertension and cognitive disorders, on the basis of testing data by the SF-36 scale, there was a significant (p<0.001) decrease in quality of life on all scales as compared with healthy ones on average by 24.5-66.0 points.
Highlights
The calculation of total cardiovascular risk (CVR) by the SCORE scale in the study subjects showed that all patients with arterial hypertension (AH), as well as healthy individuals, had a certain risk of developing fatal cardiovascular events during 10 afteryears
The obtained data testify to the absence of significant differences relatively CVR by the SCORE scale between the studied groups of AH patients (p>0.05) and a higher incidence of high risk compared to healthy subjects (p
In working patients with controlled AH stage II non-demential cognitive impairment was detected in 32.22% of cases
Summary
Особенности когнитивных нарушений у больных артериальной гипертензией невысокого сердечно-сосудистого риска. Проанализированы особенности развития когнитивных расстройств при артериальной гипертензии во взаимосвязи с анамнезом и особенностями течения заболевания. The improvement of the prognosis of patients with arterial hypertension (AH) depends on long-term effective control of blood pressure, but diagnosis and initiation of therapy at the initial stage of the disease development, when hypertension of the target organs has not yet occurred is an important condition as well [3]. A retrospective analysis of the medical documentation of 509 able-bodied patients with a controlled AH stage II in real medical practice showed absence of any information about the CD during the dispensary follow-up of the disease. The purpose of the study is to determine the state of the cognitive sphere, the profile of cognitive impairment and the relationship with quality of life in patients with controlled arterial hypertension, stage II
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