FEATURES OF CLINICAL MANIFESTATIONS OF COVID-19 IN CHILDREN OF THE FIRST YEAR OF LIFE

Abstract

During the 3 years of the COVID-19 pandemic, the proportion of children, including children of the first year of life, increased in the structure of cases. The aim of the study is to study the features of COVID-19 in children of the first year of life during the period of active involvement of children of this age in the epidemic process. The article presents a comparative analysis of the clinical and laboratory features of COVID-19 in two observation groups: 49 children aged 1 month to one year and 61 children aged one to 10 years. Clinical symptoms of COVID-19 in infants in most cases are characterized by moderate catarrhal manifestations, normal or subfebrile temperature, absence of clinical signs of lower respiratory tract lesions and respiratory failure. According to CT scans of the chest organs, almost half of the children have lung tissue damage (mainly CT-1). According to the results of laboratory examination, the majority of patients (51-82%) have an increase and long-term preservation of pathological parameters of intracellular enzymes (ASAT, CPK, especially LDH) up to 2-3 norms, blood lactate, D-dimer. Thus, there is a discrepancy between the clinical manifestations of the disease and the detected laboratory parameters.