Abstract
Background.Digestive diseases are a leading cause of body weight deficit and has a leading position among general morbidity in young patients.Purpose.To analyze the pathology of the upper digestive tract in young men with a low body weight.Material and methods.193 young men aged 16-27 y.o. (mean age 20,3±2,2 years) with a mean body mass index (BMI) 17,8±2,4 kg/m2were examined. Erosive lesions of the stomach were found in 18,8% (n=36) and erosive lesions of the duodenum – in 16,1% (n=31). Ucer of duodenum were found in 11,4% (n=22) and none of stomach. Duodenal reflux were found in (51,8%;n=100) and every fourth was combined with erosive gastritis. Histological examination of stomach revealed an inflammation in all cases. Atrophic changes in the antral stomach were detected in 11% (n=6) of the cases. All cases of atrophy accompanied by HP colonization. In the group with normal BMI the prevalence of cardia failure, erosive lesions of the esophagus, stomach and duodenum were founded. In the same group there were prevalence of stomach inflammation by histology (44%). The patients with low BMI (hypotrophy 1 degree) have less erosion and inflammation compare to patients with normal BMI and hypotrophy 2-3 degrees.Conclusions.1. Stomach inflammation were revealed in the majority of young men with low BMI. Atrophic changes of gastric antrum associated with HP infection were found in 10% of cases. 2. Erosive lesions of the esophagus, stomach and duodenal are associated with the BMI. This finding allows use the BMI as an integral indicator of the severity of the inflammation of stomach and duodenum. Erosive lesions of the upper digestive tract are found predominantly in patients with normal BMI.
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