Features assessed on magnetic resonance images improve prediction of total knee arthroplasty in subjects with symptomatic radiographic knee osteoarthritis: data from the osteoarthritis initiative

Abstract

s / Osteoarthritis and Cartilage 22 (2014) S57–S489 S175 Results: Of 387 enrolled patients 5 were excluded due to poor quality or radiographs > 6 months leaving 382 TJR cases for inclusion. Follow-up was complete for >95% of patients. The mean (SD) age was 68.9 (9.3) years, 61% were female and the mean BMI was 29.9 (9.0). The change in HHS pain scores from baseline was 27.1 (9.6) at 1 year and 27.1 (9.5) at 2 years. When painwas dichotomised into 2 groups based on theMCID ( 5 points), 96% of patients demonstrated a clinically meaningful improvement in pain at 1 and 2 years. The change in function scores from baseline was 16.2 (10.9) and 15.9 (11.8) at 1 and 2 years. When function was dichotomised into 2 groups based on the MCID ( 6 points), 81% and 78% of patients demonstrated a clinically meaningful improvement in function at 1 and 2 years. Regression analysis demonstrated significantly lower odds of a clinically meaningful improvement in pain and function for patients with less severe baseline radiographic changes, when compared to severe changes, (mK-L 4b). Conclusions: We have demonstrated an inverse relationship between the severity of pre-operative radiographic changes and improvement in pain and function at 1 and 2 years in people undergoing primary THR for OA, and suggest that this has important clinical implications for patient selection. 296 FEATURES ASSESSED ON MAGNETIC RESONANCE IMAGES IMPROVE PREDICTION OF TOTAL KNEE ARTHROPLASTY IN SUBJECTS WITH SYMPTOMATIC RADIOGRAPHIC KNEE OSTEOARTHRITIS: DATA FROM THE OSTEOARTHRITIS INITIATIVE M.C. Hochberg y, A. Yip y, K. Favors z, J. Sorkin y, J. Martel-Pelletier x, J-P. Pelletier x. yUniv. of Maryland, Baltimore, MD, USA; zVA Maryland Hlth.Care System, Baltimore, MD, USA; xUniv. of Montreal, Montreal, QC,