Abstract

Breast cancer is one of the leading causes of death among women, more so than all other cancers. The accurate diagnosis of breast cancer is very difficult due to the complexity of the disease, changing treatment procedures and different patient population samples. Diagnostic techniques with better performance are very important for personalized care and treatment and to reduce and control the recurrence of cancer. The main objective of this research was to select feature selection techniques using correlation analysis and variance of input features before passing these significant features to a classification method. We used an ensemble method to improve the classification of breast cancer. The proposed approach was evaluated using the public WBCD dataset (Wisconsin Breast Cancer Dataset). Correlation analysis and principal component analysis were used for dimensionality reduction. Performance was evaluated for well-known machine learning classifiers, and the best seven classifiers were chosen for the next step. Hyper-parameter tuning was performed to improve the performances of the classifiers. The best performing classification algorithms were combined with two different voting techniques. Hard voting predicts the class that gets the majority vote, whereas soft voting predicts the class based on highest probability. The proposed approach performed better than state-of-the-art work, achieving an accuracy of 98.24%, high precision (99.29%) and a recall value of 95.89%.

Highlights

  • We evaluated the performances of logistic regression, support vector machine, k-nearest neighbors, stochastic gradient descent learning, naïve Bayes, random forest, and decision tree

  • The results show that support vector machine (SVM) outperformed both the decision tree and the MLP

  • Dichotomiser 3 (ID3) trees with no pruning. It makes a final prediction based on the mean of each prediction, and it tends to be robust to overfitting, mainly because it takes the average of all the predictions, which cancels out biases

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Summary

Introduction

Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. Benign: If the cells are not cancerous, the tumor is benign (not dangerous to health) It will not invade nearby tissues or spread to other areas of the body (metastasize). Some cancer cells can move into the bloodstream or lymph nodes, where they can spread to other tissues within the body, which is known as metastasis This is a tumor that is more dangerous and causes death. Invasive ductal carcinoma (IDC): It begins in the milk duct and can spread to the surrounding breast tissues It is the most common type of breast cancer. The work proposed here highlights the significance of the use of the best performing machine learning classifiers with ensembles techniques for accurate diagnosis of breast cancer.

Literature Review
Methodology
Data Pre-Processing
Dimensionality Reduction Using Correlation Analysis
Dimensionality Reduction Using Principal Component Analysis
Feature Selection by Using a Wrapper Subset Selection Method
Breast Cancer Tumor Classification
NaïVe Bayes Classification
Decision Tree
The Random Decision Forest Method
Ensemble Classification
Experimentation and Discussion
Results and Discussion
Comparison with Existing Work
Conclusions and Future Work
Full Text
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