Abstract

We aimed to establish a standardized procedure for white light gastroscopy (WLG) to screen gastric lesions including early gastric cancer (EGC) in China and to verify its efficacy and feasibility in clinical practice. A standardized WLG procedure for outpatients at nine tertiary hospitals in Beijing was established. Clinical information of the participants and details of the endoscopic procedures were recorded. A total of 1051 participants were enrolled in a baseline conventional endoscopic survey between March 2014 and December 2015, while 2156 patients were enrolled in the standardized WLG operation from January 2016 to June 2017. The procedure time of the standardized procedure was significantly longer than that of the baseline conventional procedure (P=0.003). More images were obtained during the standardized procedure compared with the baseline conventional procedure (P < 0.001). The overall detection rate of gastric lesions in the standardized procedure group was significantly higher than that in the baseline procedure group (52.5% vs 38.4%, P < 0.01). The satisfaction scores of both participants and endoscopists in the standardized procedure group were significantly higher than in the baseline procedure group. Compared with the conventional procedure, standardized WLG procedure significantly improves the detection rate of gastric lesions as well as the satisfaction score of participants and endoscopists despite its longer procedure time. It is effective and feasible in clinical practice in China for the use of currently available endoscopic equipment.

Highlights

  • There is no standardized operation procedure for white light gastroscopy (WLG)in China

  • The early Gastric cancer (GC) detection rate is defined as the ratio of the number of early GC to the total number of GC, which is a crucial indicator for cancer screening program evaluating

  • The early GC detection rate was over 80% in Japan [(5)], while it was lower than 10% in many hospitals of China [(6)]

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Summary

Introduction

There is no standardized operation procedure for white light gastroscopy (WLG)in China. We aimed to established a standardized procedure of white light gastroscopy for clinic patients screening, to verify its effect and its feasibility in clinical practice. The five-year survival rate was nearly 10%~20% for advanced stage GC patients, while it was over 90% for early stage patients [(3, 4)] It is the effective strategy with early detection, diagnosis and treatment to reduce mortality of GC. In China, there is no standardized operation procedure for WLG at present, which leads to misdiagnose for many early GC and precancerous lesions [(7)]. Through the prospective multi-center registry study, we verified the effect to improve the detection rate of gastric lesions and early gastric cancers after using the standard procedure. We confirmed the feasibility of the standard procedure by satisfaction survey for both patients and endoscopists

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