Abstract
Abstract Background Non-invasive point-of-care testing (POCT) devices for determining pre-donation haemoglobin (Hb) concentrations have been developed befitting the needs of blood donors and blood banks. This study was planned to evaluate the suitability of non-invasive devices over invasive POCT devices for blood donor Hb screening. Material and methods Pre-donation Hb in apparently 60 healthy blood donors was measured by a non-invasive spectrophotometric based method (pulse oximetry) and an invasive POCT method utilizing capillary blood (HemoCue). The performance of the devices was evaluated by comparison with the reference method, i.e. an automated cell counter (Sysmex). Results Hb was measured in prospective blood donors. Mean value of hemoglobin measured by HemoCue was 14.73 ± 1.20 g/dl which was more than the reference method (12.74 ± 1.23 g/dl). Moderate positive correlation was found between pulse oximetry & sodium azide method (p Conclusion Pulse-oximetry is a fast method with apparent advantage of eliminating pain. It shows adequate agreement with standard method of haemoglobin estimation but there is also a substantial possibility of causing ineligible donors to be accepted.
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