Feasibility of one-lung ventilation using two ventilators in a bleomycin treated patient under normoxic conditions: A case report

Abstract

Bleomycin is a chemotherapeutic agent that has been applied successfully for decades in the treatment of testicular tumors. Case reports and studies in animal models suggest that bleomycin increases the lifelong toxicity of lungs to increased oxygen concentrations, which may trigger ARDS. Therefore, the general recommendation is to keep oxygen levels as low as possible in the context of medical procedures, which opposes the necessity of high oxygen application during one-lung ventilation (OLV).