Feasibility of Living Related Liver Transplantation for Children with Biliary Atresia in Egypt: Single Institution Study

Abstract

Background/Aims : Biliary atresia (BA) has become the most common indication for liver transplantation among pediatric recipients. The aim is to characterize the outcome and feasibility of living related liver transplantation for children with biliary atresia in Egypt; a single institutional study. Patients and Methods : We retrospectively reviewed our records in the National Liver Institute (NLI) – Hospital, Menofiya University, starting from April 2003 to the end of August 2011. There were an 11 cases were transplanted for biliary atresia. All the patients received Lt. Lateral grafts. The mean graft volume was 248±88 gm and Graft Recipient Weight Ratio (GRWR) was 2.56±0.82. Results : At the end of this study 5 patients are alive. The mean Survival Duration was 31.04±28.1 months, early mortality was reported in 3 patients. Conclusion : Our results confirmed the effectiveness of LDLT for the treatment of children with biliary atresia with failed Kasai procedures. Living related liver grafts represented an excellent organ supply for these patients.