Abstract

Objective: The most common cause of treatment failure in patients with ovarian cancer is recurrence and dissemination in the peritoneal cavity, and treatment results of patients with disseminated disease are disappointed with a 5-year survival rate of only 30%. For this reason intraperitoneal (IP) delivery of chemotherapy is introduced as a new treatment option; however, the results of IP chemotherapy are still debatable because of catheter-related and IP infusion-related complications. We sought to determine whether intraoperative intraperitoneal (IP) chemotherapy with paclitaxel improves PFS and OS among patients with epithelial ovarian cancer.

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