Abstract
:Despite many decades of research and development, corneal opacity remains a leading cause of reversible blindness worldwide. Corneal transplantation and keratoprosthesis can restore corneal clarity, but both have well-known limitations. High-resolution electronic microdisplays may offer an alternative to traditional methods of treating corneal disease using an intraocular implant to project imagery onto the retina, obviating the need for a clear cornea. In this study, we review previous work and recent technologic developments relevant to the development of such an intraocular projection system.
Highlights
Despite many decades of research and development, corneal opacity remains a leading cause of reversible blindness worldwide
Corneal transplantation can be successful in many cases
In more complicated cases of chronic corneal disease or injury, or after graft failure, vascularization of the cornea may occur, which greatly increases the risk of transplant rejection due to exposure of the graft to the host’s immune system.[2]
Summary
Despite many decades of research and development, corneal opacity remains a leading cause of reversible blindness worldwide. Much better vision might be achieved if the intact retina in such patients could receive optical images from an intraocular electronic display (Fig. 1).
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