Abstract
In recombinant fermentations the plasmid loss probability per generation depends on the specific growth rate, which is related linearly to the dilution rate. A model with this feature and incomplete mixing has been studied analytically for stationary state behavior. While the kinetic parameters place upper limits on the dilution rate for a feasible stationary state in a well-mixed bioreactor, the feasible and nonfeasible regions for an incompletely mixed reactor are separated by either a straight line or a plane, whose position is determined by the mixing conditions.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
