Feasibility analysis of using the 6-degree-of-freedom ship motion simulator to establish a human seasickness model

Abstract

Objective To analyze the feasibility of using the 6-degree-of-freedom ship motion simulator （6-DOF SMS） to establish a human seasickness model,so as to provide an experimental model for further development of drugs for the prevention of seasickness or against seasickness. Methods The ship motion simulator was used to expose the subjects to acceleration and induce seasickness. Severity of seasickness was graded by Graybiel＇ s diagnostic criteria. The feasibility of using the 6-degree-of-freedom ship motion simulator （SMS） to establish human seasickness model was assessed by comparing the severity of seasickness following exposure with that of motion sickness derived from past history. Results Following exposure to acceleration in the ship motion simulator,a total of 42 subjects showed signs and symptoms of seasickness,with a seasickness incidence of 70%. No significant differences could be seen in the distribution of severity between the seasickness induced by exposure to SMS and motion sickness of past history （ P 〉 0.05 ）. Seasickness incidence induced by exposure to SMS was correlated with motion sickness of past history （ C = 0. 41,P 〈 0. 01 ）Conclusions Following exposure to acceleration in the ship motion simulator,most subjects showed symptoms of ship motion seasickness,and the human seasickness model was successfully established. Key words: Ship motion simulator; Sea Sickness model; Exposure to acceleration