Fe-BPsalan complex-catalyzed asymmetric 1,3-dipolar [3 + 2] cycloaddition reaction of N,N′-cyclic azomethine imines with α,β-unsaturated acyl imidazoles

Abstract

A practical iron-catalyzed asymmetric 1,3-dipolar cycloaddition of N,N′-cyclic azomethine imines with α,β-unsaturated acyl imidazoles was developed to afford N,N′-bicyclic pyrazolidine in good yields and excellent stereoselectivities (up to 98% ee).