FDG PET/CT of COVID-19.

Abstract

HomeRadiologyVol. 296, No. 2 PreviousNext Reviews and CommentaryFree AccessImages in RadiologyFDG PET/CT of COVID-19Sijuan Zou, Xiaohua Zhu Sijuan Zou, Xiaohua Zhu Author AffiliationsFrom the Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China.Address correspondence to X.Z. (e-mail: [email protected]).Sijuan ZouXiaohua Zhu Published Online:Mar 6 2020https://doi.org/10.1148/radiol.2020200770MoreSectionsPDF ToolsImage ViewerAdd to favoritesCiteTrack Citations ShareShare onFacebookTwitterLinked In A 55-year-old male smoker in Wuhan, China, developed intermittent fever, fatigue, and dry cough for 5 days. The initial chest CT findings from an outside institution suggested lung malignancy. Fluorine 18 fluorodeoxyglucose (FDG) PET/CT was performed for further evaluation.The PET maximum intensity projection image (Figure, part A) depicted an FDG-avid mass with a maximum standardized uptake value of 4.9 in the right lung. Increased accumulation of FDG was noted in the right paratracheal and right hilar lymph nodes as well as in bone marrow. Axial images (Figure, parts B, C) showed ground-glass opacities with areas of focal consolidation primarily in the right upper lobe and a focal opacity in the left upper and right middle lobes. Influenza, respiratory syncytial virus, and other common respiratory virus infections were excluded using nasopharyngeal swab tests.A, PET maximum intensity projection image shows a fluorine 18 fluorodeoxyglucose (FDG)–avid mass (arrow) with a maximum standardized uptake value of 4.9 in the right lung. Increased accumulation of FDG in the right paratracheal, right hilar lymph nodes (arrowheads), and bone marrow are also noted. B, Low-dose axial CT scan and, C, PET/CT fusion image show ground-glass opacities with areas of focal consolidation (black arrow) primarily in the right upper lobe and a focal opacity in the left upper and right middle lobes (white arrows). D, Follow-up CT scan obtained 4 days later demonstrates progression of lesions in bilateral upper and right middle lobes (arrows) with newly developed focal opacities in the left upper and lower lobes (arrows).Download as PowerPointOpen in Image Viewer Follow-up CT 4 days later revealed progression of lesions in the bilateral upper and middle lobes with newly developed focal opacities in the left upper and lower lobes (Figure, part D) (1,2). One week later, severe acute respiratory syndrome coronavirus 2 infection was confirmed by means of real-time fluorescence polymerase chain reaction confirming coronavirus disease 2019 (COVID-19). After 10 days of treatment, the patient was considered recovered from COVID-19 and was discharged.Disclosures of Conflicts of Interest: S.Z. disclosed no relevant relationships. X.Z. disclosed no relevant relationships.Supported by the National Natural Science Foundation of China (grants 91959119, 81873903, and 81671718) and the Clinical Foundation of Tongji Hospital (grant 2015C013).