Favorable outcomes in Hispanic recipients receiving simultaneous pancreas kidney transplantation.

Abstract

The objective of this study was to compare the long-term outcomes of Hispanic versus white recipients who underwent simultaneous pancreas kidney transplantation (SPKT). This single-center study, conducted from 2003 to 2022, had a median follow-up of 7.5years. The study included 91 Hispanic and 202 white SPKT recipients. The mean age (44 vs. 46years), percentage of males (67% vs. 58%), and body mass index (BMI) (25.6 vs. 25.3kg/m2 ) were similar between the Hispanic and white groups. The Hispanic group had more recipients with type 2 diabetes (38%) compared to the white group (5%, p<.001). The duration of dialysis was longer in Hispanics (640 vs. 473days, p=.02), and fewer patients received preemptive transplants (10% vs. 29%, p<.01) compared to whites. Hospital length of stay, rates of BK Viremia, and acute rejection episodes within 1year were similar between the groups. The estimated 5-year kidney, pancreas, and patient survival rates were also similar between the groups, 94%, 81%, and 95% in Hispanics, compared to 90%, 79%, and 90% in whites. Increasing age and longer duration of dialysis were risk factors for death. Although Hispanic recipients had a longer duration on dialysis and fewer preemptive transplants, the survival rates were similar to those of white recipients. However, referring providers and many transplant centers continue to overlook pancreas transplants for appropriately selected patients with type 2 diabetes, particularly among minority populations. As a transplant community, it is crucial that we make efforts to comprehend and tackle these obstacles to transplantation.