Abstract
Background: The finding of fatty liver disease (FLD) has generally been assumed to be a consequence of ethanol ingestion. However, non- alcoholic fatty liver disease (NAFLD) was identified as a specific entity. Although FLD is generally nonprogressive or only slowly progressive, cirrhosis and HCC can develop. Objectives: The aim of this study is to find out the prevalence, clinical presentation and aetiology of FLD in Sudanese patients. Methods: This is a descriptive cross sectional study which included 100 patients with FLD detected by ultrasonography at the national center for gastro-intestinal and liver diseases. Data was collected using a well designed questionnaire and results were analyzed by using SPSS computer system. Results: Out of 1800 patients with liver disease, 100 were found to have FLD. These have no sex difference. Their mean age was 49.8 ±15.2 years. The main presenting symptoms were upper abdominal pain (60%) and fatigability in (41%). while (7%) were asymptomatic. Hepatomegaly was clinically detected in (44%). Ninety out of these 100 patients had non alcoholic fatty liver disease (NAFLD). In this group (42%) were diabetics and (55%) had hyperlipidemia. A BMI of > 25kg/m2 was detected in 47% of patients. In patients with FLD and a BMI
Highlights
Fatty liver disease (FLD) is a chronic disease that affects a high proportion of the world’s population
Fifty- Five (55%) patients were female with male to female ratio of 1:1.2 while the ratio is 1: 3 and 1: 1 in primary and secondary non- alcoholic fatty liver disease (NAFLD) respectively
Was clinically detected in 44(44%) patients
Summary
Fatty liver disease (FLD) is a chronic disease that affects a high proportion of the world’s population. The finding of fatty liver has generally been assumed to be a consequence of ethanol ingestion. The finding of fatty liver disease (FLD) has generally been assumed to be a consequence of ethanol ingestion. Non- alcoholic fatty liver disease (NAFLD) was identified as a specific entity. Results: Out of 1800 patients with liver disease, 100 were found to have FLD. Ninety out of these 100 patients had non alcoholic fatty liver disease (NAFLD). In this group (42%) were diabetics and (55%) had hyperlipidemia. Conclusion: Fatty liver disease is not uncommon in Sudan and most of the patients’ diseases are non-alcohol related
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