Abstract
THERE IS A HIGH prevalence of cardiovascular disease among long-term renal transplant recipients. Its etiology is multifactorial, though hyperlipidemia has been identified as one of the most important risk factors. The atherogenic capacity of the lipoproteins is conditioned by the fatty acid composition of their lipid component. The balance in the concentration of polyunsaturated and monounsaturated fatty acids in low-density lipoproteins (LDL) influences the susceptibility of the LDL particles to oxidation. The fatty acid content of the various lipid fractions has not been extensively studied in renal transplant recipients. The aim of the study was to analyze the fatty acid distribution in the LDL fraction of renal transplantation patients treated with cyclosporine-neoral.
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