Abstract

Identificar fatores associados ao câncer da pele não melanoma em Taubaté-SP. Estudo caso-controle de base hospitalar com residentes em Taubaté atendidos entre 01/01/05 e 31/12/06. Os indivíduos foram combinados 1:1 conforme gênero e idade. Foram variáveis independentes: idade, gênero, fototipo, ascendência europeia, tempo de moradia, exposição solar, tempo (em anos), número de horas e horário de exposição solar ocupacional e não ocupacional, fotoproteção, histórico familiar e fotodano. Foi utilizada a regressão logística hierarquizada em três níveis. O ajuste do modelo foi realizado pelo teste de Hosmer-Lemeshow e sua acurácia foi verificada pela curva ROC. O nível de significância foi p < 0,05. Foram 132 casos e 132 controles. Compuseram o modelo final: fototipo com OR = 3,14 (IC 95% 1,79–5,49), horas de exposição solar ocupacional 1,76 (1,04–2,99) e não ocupacional 1,80 (0,98–3,29) e histórico familiar 2,10 (1,13–3,93).Teste de Hosmer-Lemeshow, p = 0,97. Acurácia 70% (IC 95% 63–76). Pele clara, histórico familiar e exposição solar ocupacional e não ocupacional se associaram ao câncer cutâneo não melanoma em Taubaté-SP. To identify factors associated with non-melanoma skin cancer in the city of Taubaté, São Paulo, Brazil. Hospital-based case-control study with individuals residing in Taubaté, treated between January 2005 and December 2006. The subjects were matched 1:1 according to gender and age. Age, gender, phototype, European descent, time of residence, sun exposure, time (in years), number of hours and time of occupational and non-occupational sun exposure, photoprotection, family history and photodamage were independent variables. A hierarchical logistic regression was used at three levels. The model adjustment was performed using the Hosmer-Lemeshow test and its accuracy was verified by ROC curve. The significance level was p < 0.05. There were 132 cases and 132 controls. Phototype with OR = 3.14 (95% CI 1.79–5.49), hours of occupational 1.76 (1.04–2.99) and non-occupational sun exposure 1.80 (0.98–3.29) and family history 2.10 (1.13–3.93) were the variables in the final model. Hosmer-Lemeshow test, p = 0.97. Accuracy 70% (95% CI 63–76). We concluded that fair skin, family history and occupational and non-occupational sun exposure were associated with non-melanoma skin cancer in Taubaté-São Paulo.

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