Fatores associados à dislipidemia na pós-menopausa

Abstract

to evaluate factors associated with women's dyslipidemia during menopause. case-control study of prevalent cases and controls selected from a dedicated outpatient clinic. From recent biochemical parameters found in patients' files, women have been grouped in 'case' and 'control'. Women who presented any alteration in the blood levels of total cholesterol, LDL-cholesterol, triglycerides and/or HDL-cholesterol were considered as case, and the ones who presented normal levels of them, as control. Data concerning socioeconomic situation, physical activity, etilism and tabagism, anthropometric measurements and food ingestion have been collected and then compared between the groups. Ratios have been compared by the chi2, Fisher's exact test and/or t-Student test, depending on the distribution type. The crude relationship between each factor and the presence of dyslipidemia has been estimated by logistic regression. data have been collected from 84 women aged from 42 to 59 years, as 45 of them were grouped as case (dyslipidemic) and 39 as control (non-dyslipidemic). Age average of cases and controls was 52.1+/-4.2 and 52.2+/-4.7 years old, respectively. The sample showed to be homogeneous for the socioeconomic characteristics (income, occupation and schooling), physical activity practice, etilism and tabagism, and food ingestion, with no significant correlation with dyslipidemia. The groups presented an income up to two minimal wages, low schooling level (up to the fourth grade of lower school), and the housewife occupation. Smoking and drinking alcohol was not very frequent. Practicing physical activity was non-existent, thus characterizing a sedentary population. Food ingestion was adequate for carbohydrates, protein, lipids, but not for cholesterol (excessive) and fibers (insufficient), in both groups. Concerning the anthropometric evaluation, there has been an association with dyslipidemia, as the body mass index (BMI) and the waist circumference (WC) were significantly larger in case than in control. The waist-hip ratio has been similar in both groups. Weight excess has been found in most of the cases (73.3%) as almost half of them (44%) presented WC >88 cm, which represents a very increased risk. it is possible to conclude that, in the studied sample, only the anthropometric measurements have been considered as risk factors associated with dyslipidemia, during post-menopause.