Abstract

weight decreased from pre-treatment (91.1) to post-treatment (87.7). The median BMI decreased from 36.9 to 34.7. In the control arm, there was a slight increase in body weight from 88.2 to 88.3 but decrease in BMI from 35.2 to 34.8 but was not significant (p = 0.322). In the liraglutide arm, there was a significant reduction in SBP from 129 pre-treatment to 118 post-treatment (p = 0.018) and waist circumference 99.5—96 (p = 0.006), both these parameters shown no change in the control arm. Conclusion: Liraglutide, with diet and exercise cause meaningful weight loss and reduced SBP in non-diabetic obese binge-eating subjects.

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