Abstract

Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central nervous system that leads to permanent disability and many neurological symptoms, making everyday functioning difficult. The predictors of the acceptance of illness and the health-related quality of life in people with MS include the degree of disability, neurological symptoms and psychosocial factors, such as personal resources. The aim of our study is to determine the relationships among disability, fatigue, self-efficacy, acceptance of illness and quality of life. The study group consisted of 137 people diagnosed with multiple sclerosis—73 women and 64 men. EDSS, GNDS, LSES, AIS and MSIS-29 were used in the present study. The results show that all tested variables were significantly correlated with each other. Disability and fatigue were significant predictors of both the physical and psychological aspects of patients’ quality of life. Self-efficacy was a significant predictor of both the acceptance of illness and the psychological aspect of patients’ quality of life. Based on the current research study, it can be concluded that factors of a biomedical nature explain other aspects of struggling with the disease, rather than psychological resources.

Highlights

  • IntroductionMultiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system

  • Multiple sclerosis is a disease associated with significant challenges

  • The present study shows that disability and fatigue are important predictors of both the physical and mental aspects of quality of life

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Summary

Introduction

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. MS is the leading cause of non-traumatic neurological disability in young and middle-aged people. MS is a disease with a varied clinical course. In some people, it is mild or asymptomatic; there are forms of the illness that are rapid and lead to significant disability in a short time. There are four main forms of multiple sclerosis, namely, relapsing–remitting, primary progressive, secondary progressive and relapsing–progressive. In patients with multiple sclerosis, all symptoms associated with damage to the central nervous system may appear [1,2,3]

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