Abstract
Letters and Corrections15 February 1990Fatal Quinine-Induced ThrombocytopeniaJoel P. Freiman, MD, MPHJoel P. Freiman, MD, MPHSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-112-4-308 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: Quinine sulfate is widely used for the treatment of nocturnal leg cramps, although studies (1-3) have shown it to be of minimal benefit. One of the most serious and well-recognized side effects of quinine sulfate is thrombocytopenia. The mechanism of this reaction appears to be the formation of drug antibody complexes with an affinity for some component of the platelet membrane (4). The Food and Drug Administration (FDA) has received two reports of fatal quinine-induced thrombocytopenia.Patient 1, a 41-year-old woman, initially presented with sudden onset of severe abdominal pain radiating to her back. She had marked...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
