Abstract

A fatal case of enterovirus 71 infection with pulmonary edema and rhombencephalitis occurred in Brest, France, in April 2007. The virus was identified as subgenogroup C2. This highly neurotropic enterovirus merits specific surveillance outside the Asia-Pacific region.

Highlights

  • A fatal case of enterovirus 71 infection with pulmonary edema and rhombencephalitis occurred in Brest, France, in April 2007

  • The enterovirus strain isolated in cell culture was sent to the French National Reference Centre for Enteroviruses, where it was identified as Enterovirus 71 (EV71) by partial viral protein (VP) 1 sequencing (7)

  • Acute pulmonary edema in EV71 infections was rarely reported before the 1998 outbreak in Taiwan (12)

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Summary

Introduction

A fatal case of enterovirus 71 infection with pulmonary edema and rhombencephalitis occurred in Brest, France, in April 2007. The Case-Patient In April 2007, a 17-month-old boy was referred to the pediatric emergency ward of the Brest University Hospital. He was readmitted to the pediatric emergency unit 12 hours later, in severe respiratory distress. After the onset of this acute respiratory distress syndrome, a second chest radiograph showed marked lung infiltration.

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