Abstract

Fatal Balamuthia mandrillaris Meningoencephalitis in the Netherlands after Travel to The Gambia.

Highlights

  • Antimicrobial drug resistance is a major global problem that is likely to be exacerbated in places with poor sanitation and intensive use of antimicrobial drugs in humans and animals

  • A review of published literature and informal communication indicates that our observation of ciprofloxacin resistance in S. sonnei infections associated with travel to India is part of a general global trend

  • This increasing resistance suggests that ciprofloxacin may no longer be suitable for empiric therapy for S. sonnei infection, for patients with a history of travel to the subcontinent of India

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Summary

Introduction

Antimicrobial drug resistance is a major global problem that is likely to be exacerbated in places with poor sanitation and intensive use of antimicrobial drugs in humans and animals. A review of published literature and informal communication indicates that our observation of ciprofloxacin resistance in S. sonnei infections associated with travel to India is part of a general global trend. This increasing resistance suggests that ciprofloxacin may no longer be suitable for empiric therapy for S. sonnei infection, for patients with a history of travel to the subcontinent of India.

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