Fat suppression for ultrashort echo time imaging using a single-point Dixon method.

Abstract

In ultrashort echo time (UTE) imaging, fat suppression can improve short T2 * contrast but can also reduce short T2 * signals. The conventional two-point Dixon (2p-Dixon) method does not perform well due to short T2 * decay. In this study, we propose a new method to suppress fat for high contrast UTE imaging of short T2 tissues, utilizing a single-point Dixon (1p-Dixon) method. The proposed method utilizes dual-echo UTE imaging, where UTE is followed by the second TE, chosen flexibly. Fat is estimated by applying a 1p-Dixon method to the non-UTE image after correction of phase errors, which is used to suppress fat in the UTE image. In vivo ankle and knee imaging were performed at 3T to evaluate the proposed method. It was observed that fat and water signals in tendons were misestimated by the 2p-Dixon method due to signal decay, while the 1p-Dixon method showed reliable fat and water separation not affected by the short T2 * signal decay. Compared with the conventional chemical shift based fat saturation technique, the 1p-Dixon based approach showed much stronger signal intensities in the Achilles, quadriceps, and patellar tendons, with significantly improved contrast to noise ratios (CNRs) of 11.8±2.2, 16.0±1.6, and 26.8±1.3 with the 1p-Dixon method and 0.6±0.2, 4.6±1.0, and 17.5±1.4 with regular fat saturation, respectively. The proposed 1p-Dixon based fat suppression allows more flexible selection of imaging parameters and more accurate fat and water separation over the conventional 2p-Dixon in UTE imaging. Moreover, the proposed method provides much improved CNR for short T2 tissues over the conventional fat saturation method.