Abstract
Purpose: Osteoarthritis (OA) is the most common joint disease with a great impact on the quality of life. Obesity and the related metabolic disease are main risk factors, in which low-grade systemic inflammation is an important regulator. In this regard, the infrapatellar fat pad (IPFP) also came forward as a local OA joint tissue, contributing to and influenced by inflammatory responses in the OA knee.
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