Abstract
Based on its described beneficial effects on small and large intestinal epithelium, butyrate can be a very good alternative to antimicrobial growth promoters. Effective dietary application requires coating because the majority of uncoated butyrate is purportedly absorbed before reaching the proximal small intestine. Several studies using different protocols reported varying stomach passage times in chickens. In the present study, we compared feeding uncoated vs. fat coated [1-13C] labeled Ca butyrate, and compared the effect of butyrate coating with [1-13C] labeled octanoic acid which is an established indicator of stomach passage. By monitoring 13CO2 expiration continuously, we show that the majority (about 80%) of uncoated Ca butyrate is oxidized proximally of the small intestine, and that base line levels were reached after 6h. Fat coating of Ca butyrate resulted in reduced proximal oxidation (from about 80% to about 45%), and in an extended release pattern of 13CO2 from butyrate similar to that of octanoic acid, and that the return to base line levels was extended to 12h. This indicated that fat coating of butyrate results in absorption along the entire intestinal tract in broilers, offering an explanation for the described beneficial effects as a growth promoter.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.