Abstract

BackgroundStorage of genomic data is a major cost for the Life Sciences, effectively addressed via specialized data compression methods. For the same reasons of abundance in data production, the use of Big Data technologies is seen as the future for genomic data storage and processing, with MapReduce-Hadoop as leaders. Somewhat surprisingly, none of the specialized FASTA/Q compressors is available within Hadoop. Indeed, their deployment there is not exactly immediate. Such a State of the Art is problematic.ResultsWe provide major advances in two different directions. Methodologically, we propose two general methods, with the corresponding software, that make very easy to deploy a specialized FASTA/Q compressor within MapReduce-Hadoop for processing files stored on the distributed Hadoop File System, with very little knowledge of Hadoop. Practically, we provide evidence that the deployment of those specialized compressors within Hadoop, not available so far, results in better space savings, and even in better execution times over compressed data, with respect to the use of generic compressors available in Hadoop, in particular for FASTQ files. Finally, we observe that these results hold also for the Apache Spark framework, when used to process FASTA/Q files stored on the Hadoop File System.ConclusionsOur Methods and the corresponding software substantially contribute to achieve space and time savings for the storage and processing of FASTA/Q files in Hadoop and Spark. Being our approach general, it is very likely that it can be applied also to FASTA/Q compression methods that will appear in the future.AvailabilityThe software and the datasets are available at https://github.com/fpalini/fastdoopc

Highlights

  • Storage of genomic data is a major cost for the Life Sciences, effectively addressed via specialized data compression methods

  • Disk space and reading time savings apply to the Apache Spark framework, when used to process FASTA/Q files stored on the Hadoop File System

  • The intent of Experiments 1-3 is to provide evidence of the space and time performance advantages deriving from the adoption of specialized FASTA/Q compressors within MapReduce-Hadoop

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Summary

Introduction

Storage of genomic data is a major cost for the Life Sciences, effectively addressed via specialized data compression methods. The relation between Big Data Technologies and FASTA/Q data compression in bioinformatics Due to the same reasons of massive data production, the development and use of Big Data Technologies for Genomics and the Life Sciences, have been indicated as directions to be actively pursued [9], with MapReduce [10], Hadoop [11] and Spark [12] being the preferred ones [13]. Processing files compressed using a non-splittable format is still possible under Hadoop, but at a cost of very long decompression times (data not shown but available upon request). Further discussion on those topics is in section “Preliminary”. We refer to the former category of data compressors as splittable Codecs

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