Abstract
Very high temporal and spatial resolution is mandatory for the diagnosis of arteriovenous malformations (AVM) of the hand. Until now, magnetic resonance imaging (MRI) has not fulfilled both requirements simultaneously. This study presents how the combination of a very fast TWIST MRI (time-resolved angiography with interleaved stochastic trajectories) sequence and iterative reconstructions optimizes temporal as well as spatial resolution. 11 patients were examined at a 3-T MRI scanner with two different TWIST protocols: the standard and the study protocol, acquiring a data set every 5.57 s and 1.44 s respectively. The study data was retrospectively iteratively reconstructed with different regularization factors (0.001, 0.002, 0.004, 0.008). Results were compared using the sign-test. P-values < 0.05 were regarded statistically significant. With a low amount of contrast medium, the temporal resolution of the study protocol enabled the differentiation of arteries from veins in all patients whereas the signal-to-noise ratio (SNR) deteriorated. Depending on the regularization factors, SNR, delineation of arterial feeders and non-involved hand and interdigital arteries, as well as artefact levels varied. Overall, iterative reconstruction with regularization factor 0.004 achieved the best results, consequently showing the ability of MRI as a reliable diagnostic method in AVMs of the hand.
Highlights
Very high temporal and spatial resolution is mandatory for the diagnosis of arteriovenous malformations (AVM) of the hand
Representing the most common type of high-flow malformations, peripheral arteriovenous malformations (AVMs) are very rare and occur in 14.3% of patients suffering from vascular malformations[4]
Thereby, we examined the value of the study TWIST MRA in improving the temporal resolution in high-flow vessels
Summary
Very high temporal and spatial resolution is mandatory for the diagnosis of arteriovenous malformations (AVM) of the hand. This study presents how the combination of a very fast TWIST MRI (time-resolved angiography with interleaved stochastic trajectories) sequence and iterative reconstructions optimizes temporal as well as spatial resolution. As the blood flow in AVMs is very fast and diameters of vessels may be very small, the perfect imaging modality for intervention planning needs to combine an extremely high temporal and a high spatial resolution[10,11]. Both can be achieved with conventional digital subtraction angiography (DSA)[11,12,13].
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