Abstract

Circulating cell-free deoxyribonucleic acid (cfDNA) originates from cells undergoing necrosis and apoptosis or after active secretion and is constantly found in the blood stream. Elevated cfDNA has been reported in pathological conditions, including infections, malignancies and autoimmunity (1-3). We developed a simple fluorescent method to directly measure cfDNA concentrations in biological samples, without prior processing, in clinical laboratories (4).

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