Abstract
A cobalt metal organic framework was prepared with rapid ultrasound assisted method by treatment of cobalt nitrate with pyridine 2,6-dicarboxilic acid dissolved in ethanolic media and used as a sorbent for pipette tip solid phase extraction of Bisphenol A (BPA) and its determination in spiked juice and drinking water samples by HPLC. Parameters which influence extraction efficiency such as pH, sample volume, amount of sorbent, type and volume of eluent, and number of draw/eject cycles for extraction and elusion were tested and optimized. Results showed that best extraction efficiency could be obtained at pH 3, 150 µL of sample volume, 3 mg of adsorbent and 10 µL of methanol as elution solvent. Numbers of draw/eject cycles for both sample extraction and elution were 7 cycles. Limit of detection and limit of quantification of this method were 0.07 and 0.3 µg L -1 , respectively, with linear dynamic range of 0.3 to 300 µg L -1 for BPA. This method was applied successfully for determination of BPA in five spiked juices and drinking water samples. KEY WORDS : Cobalt metal organic framework, Bisphenol A, Pipette-tip solid phase extraction, Juice analysis Bull. Chem. Soc. Ethiop. 2018 , 32(3), 595-602. DOI: https://dx.doi.org/10.4314/bcse.v32i3.17
Highlights
Bisphenol A (BPA) has many application in the production of polymeric compound such as poly vinyl chloride (PVC) and polycarbonate [1]
Common problem in usage of such devices is migration of BPA to the environmental ecosystems or food samples that can harmful for consumers due to the affecting the hormonal system of humans and animals, even at low concentrations [2,3,4]
In one of our previous reports, we fully described how the assembly of pipette tip and its uniform packing was performed [20]. 3 mg of Co-metal organic frame work (MOF) sorbent was packed in a 10 μL pipette tip (Dragon, China) as a micro-column and connected to the end of a 200 μL variable sampler (Isolab, Germany)
Summary
Bisphenol A (BPA) has many application in the production of polymeric compound such as poly vinyl chloride (PVC) and polycarbonate [1]. A Co based metal organic framework is synthesized and used as adsorbent for extraction and high performance liquid chromatographic (HPLC) determination of BPA. After optimizing affecting parameters on extraction efficiency, this method was applied for determination of BPA in juice and drinking water samples.
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