Abstract
We implement a near-infrared (NIR) version of compressive Raman imaging that incorporates a digital micromirror device (DMD) and a single-pixel detector for fast chemometric analysis and microscopic imaging. The NIR compressive Raman system is successfully used to detect and image active pharmaceutical ingredients exhibiting polymorphism within compact pharmaceutical tablets. We report the chemical imaging of a mixture of two clopidogrel polymorphs and three excipients in solid tablets with a pixel dwell time of 2.5 ms (0.5 ms per species). These results open the road to fast pharmaceutical tablet quality control imaging using compressive Raman technology.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.