Abstract
Mitigation of the global threat associated with antibiotic-resistant microbes necessitates effective preventative measures. One such strategy relies on self-disinfecting anionic block polymers that undergo a water-activated surface pH drop, which kills over 99.9999% of various microbes in minutes. In this work, we elucidate the time-dependent morphological response of Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria to this polymer surface. Since pre-exposure of the polymer to solvent-vapor or hydrothermal annealing alters the tortuosity of pathways responsible for proton diffusion, corresponding changes in bacterial inactivation kinetics are compared and analyzed in the context of a model capable of differentiating between single-stage and more complex inactivation processes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
