Abstract
This study was designed to measure the velocity of axonal transport of choline-containing lipids in sensory and motoneurones of control rats and rats with streptozotocin-induced diabetes of 3 weeks duration. An additional experiment was performed in which nerves from control and diabetic rats were maintained in vitro during the period between injection of isotope in the nerve cell body region and arrest of transport. This was done to preclude the effects of temperature differences between controls and diabetics. None of these experiments revealed defects of velocity of fast orthograde transport of labelled lipids in the diabetic rats. The results indicate that short-term experimental diabetes has no effect on the velocity of fast anterograde axonal transport of choline-containing lipids. The findings are discussed in relation to similar studies on the fast anterograde axonal transport of proteins.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
