Farmakologisk behandling av psykotiska patienter med svåra produktiva symtom En retrospektiv undersökning

Abstract

The treatment of patients with severe productive psychotic symptoms, aggressiveness, and lack of insight is often problematic. Prompt neuroleptic treatment with high doses during the initial phase followed by consistent maintenance treatment to prevent relapses is recommended in such cases. In a retrospective study of this treatment strategy, several positive effects were registered, e.g. rapid neuroleptisation, rapid reduction of anxiety and aggressiveness, a marked decrease of traumatic incidences in connection with drug administration to uncooperative patients (depot form of the drug), a minimum of psychotic experiences and, consequently, a minimum of “psychotic learning”. Shorter hospital treatment periods with improved opportunities for rapid rehabilitation were also achieved. Although the patients included in this study suffered from comparatively severe degrees of psychosis, continuous maintenance treatment with neuroleptic drugs was found to give efficient relapse prophylaxis. High doses, neurolep...