Abstract

BackgroundTo estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of metabolic control, as well as to compare the outcome with the results of the patients treated by endocrinologists.MethodsA controlled, prospective over 30-months period study was conducted in area 7 of Madrid. One hundred twenty six eligible diabetic patients diagnosed as having peripheral vascular disease between January 2003 and June 2004 were included in the study. After a treatment period of three months by the Diabetes team at St Carlos Hospital, 63 patients were randomly assigned to continue their follow up by diabetes team (Group A) and other 63 to be treated by the family physicians (FP) at primary care level with continuous diabetes team coordination (Group B). 57 DPts from Group A and 59 from Group B, completed the 30 months follow-up period. At baseline both groups were similar in age, weight, time from diagnosis and metabolic control. The main outcomes of this study were the proportion of patients meeting ATP III and Steno goals for HbA1c (%), Cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, blood pressure, albumine-to-creatinine excretion ratio (ACR), body mass index (BMI), waist circumference (WC), anti-aggregation treatment and smoking status.ResultsAt the end of the follow up, no differences were found between the groups. More than 37% of diabetic patients assigned to be treated by FP achieved a HbA1c < 6.5%, more than 50% a ACR < 30 mg/g, and more than 80% reached low risk values for cholesterol, LDL cholesterol, triglycerides, diastolic blood pressure and were anti-aggregated, and 12% remained smokers. In contrast, less than 45% achieved a systolic blood pressure < 130 mm Hg, less than 12% had a BMI < 25 Kg.m-2 (versus 23% in group A; p < 0.05) and 49%/30% (men/women) had a waist circumference of low risk.ConclusionImprovements in metabolic control among diabetic patients with peripheral vascular disease treated at a primary health care setting is possible, reaching similar results to the patients treated at a specialized level. Despite such an improvement, body weight control remains more than poor in both levels, mainly at primary care level. General practitioner and endocrinologist coordination care may be important to enhance diabetes management in primary care settings.Trial registrationClinical Trial number ISRCTN75037597

Highlights

  • To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of metabolic control, as well as to compare the outcome with the results of the patients treated by endocrinologists

  • The median of clinical and laboratory data change at entry and during follow-up were similar among diabetic patients assigned to be treated by the diabetes team (Group A) or by family physicians (Group B) and differences between groups were not found

  • The percentage of diabetic patients achieving the blood pressure (SBP: from 21 and 24% to 51 and 43% and DBP: from 53 and 46% to 82 and 86% for Group A and B, respectively), total cholesterol (Group A, 68 vs. 93%; Group B 68 vs. 95%) and LDL cholesterol (Group A, 46 vs. 84%; Group B, 39 vs. 78%) targets increases during the follow-up, whereas glycemic control and triglycerides and HDL-cholesterol levels were maintained in both groups

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Summary

Introduction

To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of metabolic control, as well as to compare the outcome with the results of the patients treated by endocrinologists. Patients assigned to conventional treatment were treated by their general physicians (GP) These assigned to the intensive group were followed up by a specialized team at the Steno Diabetes Centre. Despite suboptimal glycemic control in both groups, GPs were unable to achieve low-risk values in a similar percentage of patients as the specialized centre, indicating scope for diabetes management at primary care level to be improved. Surveys in Spain revealed that metabolic control of diabetic subjects treated at primary care level [10,11,12,13,14,15] was worse than in diabetes centres [16,17].

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