Abstract
The hypopituitarism of children, partial or absolute, stems from many causes. Tumor cause, such as craniopharyngioma, is predominant and must always be sought. The presence of a pituitary lesion in a child with a GH deficiency, especially in family forms, should not overlook the possibility of a concomitant genetic disorder, in particular mutation of Prop 1. Surgical abstention in this case, with morphological and ophthalmologic monitoring are shown because the spontaneous regression of the hyperplasia pseudo tumor . We report two cases in this clinical regard. Keywords: pituitary insufficiency, GH deficiency, pituitary hyperplasia, Mutation of Prop. 1.
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