Abstract
Background A points-based scoring system defines levels of familial risk for colorectal neoplasia. More than 7 points defines a high-risk group that should undergo colonoscopy every 3 years. Family History Scoring was applied to families fulfilling Amsterdam I criteria and familial colorectal cancer type X to compare colon cancer risk. Methods Amsterdam I (AmI) and familial type X (famX) families identified from Jagelman Registry database were scored. Affected probands (AP), unaffected probands (UP), affected sibling (AS), and unaffected sibling (US) of the proband, and a child of each sibling were scored. Median, range, and standard deviation were compared for each syndrome to determine level of risk. Results
Highlights
A points-based scoring system defines levels of familial risk for colorectal neoplasia
History Scoring was applied to families fulfilling Amsterdam I criteria and familial colorectal cancer type X to compare colon cancer risk
Amsterdam I (AmI) and familial type X families identified from Jagelman Registry database were scored
Summary
A points-based scoring system defines levels of familial risk for colorectal neoplasia. More than 7 points defines a high-risk group that should undergo colonoscopy every 3 years. History Scoring was applied to families fulfilling Amsterdam I criteria and familial colorectal cancer type X to compare colon cancer risk
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