Abstract
Object: The aim of this study was to describe a familial dyslipidemia revealed by a corneal arch. Familial hypercholesterolemia is a rare and severe hereditary dyslipidemia with an exceptional homozygous form. He was a 43-year-old patient admitted with visual disturbance, xanthomatous papule and orange coloring at the level evolving for 5 years, no personal history of cardiovascular disease, having a family history of lipid disorders in siblings, as a cardiovascular risk factor: age over 50 and the male gender, normal cardio pulmonary examination, blood pressure at 120/80 mmhg, heart rate 78 bpm, in whom the ophthalmological examination shows a yellowish spot on the cornea (Figure 1). We report the case of familial dyslipidemia revealed by a corneal spot in Guinea.More recent studies increasingly suggest that it is much more widespread than previously thought: 1/200 to 1/400. Familial dyslipidemia is a rare and severe metabolic abnormality. It should be screened as early as possible like any other cardiovascular risk factor for atheroma to avoid the occurrence of a major cardiovascular event.
Highlights
IntroductionFamilial hypercholesterolemia is a rare and severe hereditary dyslipidemia with an exceptional homozygous form [1]
Familial hypercholesterolemia is a rare and severe hereditary dyslipidemia with an exceptional homozygous form. He was a 43-year-old patient admitted with visual disturbance, xanthomatous papule and orange coloring at the level evolving for 5 years, no personal history of cardiovascular disease, having a family history of lipid disorders in siblings, as a cardiovascular risk factor: age over 50 and the male gender, normal cardio pulmonary examination, blood pressure at 120/80 mmhg, heart rate 78 bpm, in whom the ophthalmological examination shows a yellowish spot on the cornea (Figure 1)
We report the case of familial dyslipidemia revealed by a corneal spot in Guinea
Summary
Familial hypercholesterolemia is a rare and severe hereditary dyslipidemia with an exceptional homozygous form [1]. It is a very rare pathology (1% of hypercholesterolaemia and 1/106 hbts in the USA) which causes 100% mortality at 30 years according to BAKER SG [2]. It is responsible for severely high cholesterol levels (> 300 mg/dl) from birth and for a dramatically early risk of vascular, cardiac or cerebral complications from the age of 30 in men, and 40 in women [3]. The aim of this study was to describe a familial dyslipidemia revealed by a corneal arch
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