Abstract
Familial Mediterranean fever (FMF) is an autosomal recessively inherited autoinflammatory disease which is clinically manifested with periodic episodes of fever, polyserositis and arthritis. Among the Turkish, Arabic, Armenian and Jewish population the incidence rate ranges between 1 in 500 to 1000. The severity of the disease depends mostly on the MEFV gene mutation variations.
Highlights
Familial Mediterranean fever (FMF) is an autosomal recessively inherited autoinflammatory disease which is clinically manifested with periodic episodes of fever, polyserositis and arthritis
ConclusionThe diagnosis of childhood Familial Mediterranean fever (FMF) is frequently encountered in our country. The most severe clinical presentation occurs as a result of M694V and other exon 10 region mutations
Summary
Familial Mediterranean fever (FMF) is an autosomal recessively inherited autoinflammatory disease which is clinically manifested with periodic episodes of fever, polyserositis and arthritis. The severity of the disease depends mostly on the MEFV gene mutation variations
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