Familial dominant drusen (Malattia leventinese / Doyne honeycomb retinal dystrophy)

Abstract

Familial dominant drusen is an autosomal dominant, progressive retinal disorder characterized by central retinal drusen which often coalesce to form a honeycomb pattern. It is usually bilateral and occurs in early adulthood. Early diagnosis and follow up is essential as occurrence of choroidal neovascularisation is a possibility. Currently there is no effective treatment for this condition. Genetic counselling and molecular diagnosis are recommended.