Abstract
BackgroundMeasuring thyroid hormone levels is essential and helpful in the diagnosis of thyroid diseases.Case presentationWe had a patient with undetectable serum TSH level by the Siemens immunoassay, whereas by ELISA and Roche-Abott immunoassay, serum level of TSH was in the normal range.ConclusionIf the result of TSH level revealed very low or undetectable through one specific method, it should not be considered necessarily as a symptom of hyperthyroidism. It is to be requested to measure by the other methods with other devices too.
Highlights
BackgroundEspecially Thyroidstimulating hormone (TSH) is essential and helpful in the diagnosis of thyroid dysfunction or diseases
Measuring thyroid hormone levels is essential and helpful in the diagnosis of thyroid diseases
In the second laboratory the Enzyme-Linked Immunosorbent Assay (ELISA) method was used for measuring serum Thyroidstimulating hormone (TSH) level
Summary
Especially TSH is essential and helpful in the diagnosis of thyroid dysfunction or diseases. Case report A 24-year-old woman attended to Al-Mahdi Clinic Lab with a request for thyroid function tests and other routine checkup tests. This patient had no history of disease or symptoms of malfunctioning of thyroid gland. The patient was referred to a physician for further evaluation and her physician again requested thyroid function tests with anti-TPO With advice of his doctor, she was referred to another lab for doing these tests. In the second laboratory the ELISA method was used for measuring serum TSH level. The first laboratory negotiated with the patient for assurance and her sample was sent to a third laboratory for measurement of serum TSH level by other device with Electro Immunoassay method. Lab manager and physician in Al-Mahdi Clinic explained to the patient about the TSH variant in some people and she was assured that she was not hyperthyroid and doesn’t need any treatment
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