Abstract
A rare case of ovarian sarcoidosis with peritoneal and omental involvement presenting as an ovarian malignancy is presented. Clinical, laboratory, and radiological evaluation of the patient revealed ascites and high levels of serum CA 125 and CA 15.3. The diagnosis of sarcoidosis was confirmed with pathology findings on tissues obtained during surgical laparotomy. Establishing the diagnosis of sarcoidosis can be treacherous and was complicated in this case by the falsely elevated biomarkers and ascites.
Highlights
Atypical manifestations of sarcoidosis occurring outside typically affected organs make histology necessary in establishing the diagnosis after excluding infectious and neoplastic mimics of the disease
We present a rare case of ovarian sarcoidosis with peritoneal and omental involvement presenting as ovarian malignancy with falsely elevated cancer biomarkers
Levels of carcinoembryonic antigen were within normal range; that is, CEA levels were 1.43 ng/ml and carbohydrate antigen 19-9 (CA 19-9) levels were 6,4 U/ml
Summary
Atypical manifestations of sarcoidosis occurring outside typically affected organs make histology necessary in establishing the diagnosis after excluding infectious and neoplastic mimics of the disease. Extrapulmonary sarcoidosis has been reported in several sites; localization of the disease in the female reproductive system is extremely rare accounting for less than 1% of cases [1]. We present a rare case of ovarian sarcoidosis with peritoneal and omental involvement presenting as ovarian malignancy with falsely elevated cancer biomarkers
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