Abstract
A persistent ethical dilemma in research is the potential conflict between the patient-subject's best interests and the principles of scientific methodology. Vanderpool and Weiss discuss the problem in cancer research when a physician falsifies data in order to increase a patient's chances of being selected to participate in a clinical trial. While raising the question of whether such lying is justified if it may prolong the life of a cancer patient for whom there are no other therapeutic options, the authors point out that the inclusion of ineligible subjects may render trial results invalid.
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