Abstract

HEPATITIS associated antigen (HAA) (Australian antigen1, SH antigen2) is often demonstrable in the serum of cases of serum hepatitis. HAA is also reported in infectious hepatitis, although with lesser frequency3–5. The latter observations, however, are in contrast with the finding by Giles and co-workers6. None of the children at Willow-brook State School developed HAA in their sera after inoculation with an agent (MS–1) having the characteristics of IH virus. The apparent discrepancy can be resolved only by additional observations using specimens from epidemiologically well characterized cases.

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