Abstract

Introduction A massive promotional campaign is currently under way in behalf of Reticulose,* a substance claimed to be an antiviral biotic (The first antiviral biotic with proven clinical results). The promotional material suggests that indications for use of Reticulose are the treatment of viral and over 600 cases are quoted in which material was said to have been used successfully in a number of virus infections including herpes simplex, infectious hepatitis, encephalitis, generalized vaccinia, mumps meningitis, influenza, infectious mononucleosis, upper respiratory infections, mumps orchitis, and others. It is claimed that Reticulose has demonstrated antiviral properties. A critical review of bibliography on this material is urged by all readers of this paper. 1-5 Therapeutic results claimed in these publications will be analyzed below. The mode of action claimed by manufacturers and authors of clinical articles appears obscure. On one hand immediate relief of symptoms

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