Failure of gonadotropin-releasing hormone or human chorionic gonadotropin to enhance the fertility of repeat-breeder cows when administered at the time of insemination

Abstract

Repeat-breeder dairy cows failing to conceive to two previous inseminations were injected with saline (2 cc i.m.), gonadotropin-releasing hormone (GnRH, 2 cc i.m.) or human chorionic gonadotropin (hCG, 5000 IU i.v.) at the time of the third and succeeding inseminations. This field study involved 240 cows at three dairies. Mean conception rate was high (49.6%) for repeat-breeders, and did not differ among farms (P>0.10) or treatments (P>0.10), varying from 44.0 to 51.9% for farms and from 44.4 to 54.2% for treatments. The percentage of repeat-breeder cows bred during diestrus was very low on each of the three farms (mean = 7.9%). For this and other reasons discussed in the study, hormonal therapy was not successful in improving the conception rate of repeat-breeder cows under field conditions.