Abstract
See related article, p 958 Best currently available evidence for intracranial stenting (ICS) in intracranial atherosclerotic disease (ICAD) patients comes from secondary stroke prevention studies.1,2 However, these data do not allow any conclusion on the efficacy or safety of ICS in acute stroke patients. Chang et al3 present multicenter experiences with permanent ICS as rescue therapy after failed mechanical thrombectomy (MT) in patients with acute ischemic stroke in the carotid territory. In their study, MT failed in 148 of 591 (25%) patients with occlusions of the internal carotid artery or middle cerebral artery (M1). This rate exceeds the rate of poor recanalization of 8% to 18% as known from the large recent MT trials4–8 which at least in part might be explained by different incidence of ICAD in the trial populations. In their study, Chang et al3 observed significantly better outcomes after rescue ICS than after traditional management without increasing symptomatic intracranial hemorrhage rate or mortality (modified Rankin Scale score of 0–2; 39.6% versus 22.0%; P =0.031). The …
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